![]() This includes the sleep-wake cycle, hormone secretion, metabolism, certain behaviors, blood pressure and even our immune system. The biological clock, also known as the body clock, of the human body is responsible for governing and regulating a variety of systems in the body. Did You Know That Your Body Has an Internal Biological Clock? If the timings don’t match our normal circadian rhythms, it could result in a greater risk of various health problems. These changes also get reflected in our biological clocks, especially when it comes to times we wake up, sleep, rest, and eat. However, as a result, many businesses and professions are increasingly impacting people’s lifestyles in a variety of different ways. Global growth and progress on a variety of levels continue to move steadily forward. Because of this, any changes in behavior that cause misalignment with our biological clock can result in increased risk of various diseases. Research has shown that nearly 80% of genes in the body are regulated by the daily circadian rhythm. Applying this approach to lunar timing adaptations promises to give access to the molecular basis of circalunar clocks.In 2017, three scientists, Jeffery Hall, Michael Rosbash, and Michael Young, received the Nobel Prize in Physiology or Medicine for their discoveries regarding the molecular mechanisms in living organisms that control and propel the circadian rhythm (internal biological clock). We have shown that the heritable timing differences between strains can be exploited for genetic mapping, genome screens and comparative molecular analysis in order to identify the genes underlying local timing adaptations. In some sites along the coast several timing strains coexist in separate timing niches. Clunio marinus populations from different places are genetically adapted to the local pattern of the tides in various aspects of their circadian and circalunar clocks. While the suitable tidal situation for reproduction invariably recurs at the same time of the month and day at a given location, the timing of the tides changes tremendously along the coastline. The newly emerged adults reproduce immediately and then die in the rising tide. On these days, a circadian clock times adult emergence to the time of low tide. To achieve this remarkable synchronisation, a circalunar clock tightly regulates development and maturation of Clunio marinus, ensuring that adults can only emerge and reproduce around full or new moon. The delicate event of reproduction is strictly synchronised with the lowest low tides, which recur predictably during the spring tide days around both new and full moon. Their adult life lasts only a few hours, which are exclusively dedicated to reproduction. The non-biting midge Clunio marinus lives in the intertidal zone of the European Atlantic Coast. ![]() ![]() Our model species, the marine midge Clunio marinus (Diptera: Chironomidae), allows addressing both questions simultaneously in a highly synergistic manner. ![]() At the same time we aim to identify the molecular basis of circalunar clocks. the causes and effects of different organisms occupying different timing niches. Our research group investigates the interplay of biological clocks with evolutionary and ecological processes - e.g. However, the molecular clockworks underlying seasonal, lunar and tidal rhythms are still largely enigmatic. To date we have a good understanding of the molecular basis of circadian clocks, which control the daily rhythms of physiology and behaviour. Most organisms use endogenous biological clocks to anticipate these regular changes in their environment. Nature is structured in time by the continuous cycles of the seasons, night and day, the moon phases and the tides. ![]()
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